Although most drugs make sex worse, there are numerous drugs that can make sex better. But first we have to distinguish between two kinds of drugs. Legit drugs that are recommended or prescribed by physicians or herbalists to treat illnesses or ameliorate health conditions, and street drugs. Among legit drugs, dopamine agonists can have a positive effect on a number of parameters, primarily libido and orgasm. And then, of course, there are phosphodiesterase inhibitors like Pfizers Blue, that help erections.